Mistletoe (Viscum Album) Therapy


Scientific Information About Mistletoe (Viscum Album) Therapy

What does a therapy do? How safe are we? Where do we get our knowledge from? If we want to form our own judgment about therapy, we need the results of scientific investigations. But scientific information is constantly increasing and the results are scattered and often difficult to obtain.

These websites provide an up-to-date overview of scientific studies on the clinical use of Mistletoe (Viscum Album) therapy in cancer. Our information platform is aimed at physicians, scientists, journalists, representatives from politics, self-government and health insurances as well as at interested students and also at patients who want to orientate themselves on the current state of clinical research and important clinical observations.

These information pages are prepared and compiled according to scientific criteria. They do not contain any kind of advertisement for any preparations or companies.

Research on Mistletoe (Viscum Album) Extracts in Cancer


Complementary cancer therapies are widely used. In Europe, 40% (depending on the country 15-73%) of cancer patients use complementary therapy, mostly herbal remedies. Mistletoe (Viscum Album) extracts are most commonly found in German-speaking Central Europe (Viscum album L., UAE). Even children with cancer often receive Mistletoe (Viscum Album) therapy. Registered doctors in Germany estimate that Mistletoe (Viscum Album) therapy is mainly helpful for the treatment of cancer patients.

Biological and pharmacological effects of Viscum album L. extracts (VAE) have been extensively analyzed. Various pharmacologically active ingredients have been isolated, for example, Mistletoe (Viscum Album) lectins, viscotoxins, oligo- and polysaccharides, lipids and several others. The most striking features of VAE are its cytotoxic and growth-inhibitory effects on a variety of tumor cell lines, lymphocytes and fibroblasts in vitro. The cytotoxic effects of VAE are mainly caused by apoptosis-inducing Mistletoe (Viscum Album) lectins, while viscotoxins induce necrotic cell death. VAE are also known for their immunomodulating activity. In vitro and in vivo, they activate monocytes / macrophages, granulocytes, natural killer cells (NK cells), T cells (especially T helper cells) and induce a wide range of cytokines. VAE also stabilize DNA, reduce chromosome damage, and improve DNA repair. In animals, VAE show marked antitumoral effects. Mistletoe (Viscum Album) lectin I, an important ingredient in Mistletoe (Viscum Album) extracts, is currently also produced recombinantly and tested for use in clinical oncology. Mistletoe (Viscum Album) lectin I, an important ingredient in Mistletoe (Viscum Album) extracts, is currently also produced recombinantly and tested for use in clinical oncology. Mistletoe (Viscum Album) lectin I, an important ingredient in Mistletoe (Viscum Album) extracts, is currently also produced recombinantly and tested for use in clinical oncology.

Therapeutic Application

In cancer medicine, Mistletoe (Viscum Album)extracts are usually injected subcutaneously, but often directly into the tumor, in body cavities (intrapleural, intraperitoneal, intrapericardial) or as an intravenous infusion; occasionally they are also given orally or intravesically. In principle, all cancers are treated with Mistletoe (Viscum Album) extracts, as a sole therapy or concomitant with conventional cancer therapy (surgery, chemotherapy, radiotherapy, hormone therapy), in the curative or palliative situation, as a short therapy over a few weeks or months or as a longer therapy over several years. The dosage is either individually adjusted to the disease, the general condition, the immune status and the response to the therapy, often with additional consideration of rhythmological features, or the Mistletoe (Viscum Album)extracts are administered standardized, e.g. B. according to their lectin content.

Clinical Studies

The clinical effectiveness of Mistletoe (Viscum Album) is controversial. In order to answer these questions, a large number of clinical studies with different methodologies have been carried out in recent decades. Today, the following studies are available on Homoeopathic Mistletoe (Viscum Album)preparations: 30 prospective randomized clinical trials , 18 non-randomized prospective comparative studies , 42 retrospective comparative studies and 40 one-arm studies, If, as often happens today, only double-blind randomized controlled trials with high numbers of cases are accepted as evidence, one will not find adequate answers to many questions, even though there are now some such studies (with the restriction that double blinding does not work) Doctor or patient know whether a Mistletoe (Viscum Album) extract or a control preparation is injected, is hardly possible with subcutaneous Mistletoe (Viscum Album), since it is easily deblindable for both patient and doctor .However, those who also accept carefully conducted other types of studies - medium and small RCTs, carefully controlled comparative studies without randomized treatment allocation, cohort studies, case series - will find a wide range of interesting evidence and important clinical observations.


Mistletoe (Viscum Album) products are manufactured as an extract of Mistletoe (Viscum Album) from the relevant host trees. Many manufacturers use the Mistletoe (Viscum Album) collected in both summer and winter, while others only use the plants harvested in winter. Different extraction procedures and solvents are also used. The spectra of ingredients and active substances therefore differs in each product that is on the market. The Abnoba Company uses both summer and winter Mistletoe (Viscum Album) for the manufacture of the medicinal product in order to ensure a wide spectrum of ingredients. The Mistletoe (Viscum Album) is then extracted without exposure to air according to a patented procedure so that as a result more than 75% of the plant material used is available in the drug. All essential ingredients such as lectins, viscotoxins, polysaccharides and triterpenoids (including oleanolic acid, betulinic acid) are then contained in the extract in very high quantities. This procedure also allows the formation of Mistletoe (Viscum Album) liposomes (vesicles) which are formed from the cell membranes occurring naturally in the plant cell. These structures may be imagined as very small spheres, invisible to the naked eye, which bind or incorporate the active substances and other ingredients of Mistletoe (Viscum Album). Pure Mistletoe (Viscum Album) liposomes have an effect in their own right: they are immunologically active. This should also be taken into account in the direct effect of the product on tumour growth. The good tolerability of these products is also probably due to this.

Responsive image

German Mistletoe (Viscum Album) Sabatical

Visit to Filderstadt Klinik

Center for integrative oncology with state of art treatment facilities including Mistletoe (Viscum Album) therapy, eurythmy, external applications etc.

Further lectures on Mistletoe (Viscum Album) and its application in oncology by International experts.

Participants will be certified in Germany by one of the renowned medical doctors of the field.

Visit to Abonaba Viscum manufacturing facility.

Participate in all lectures and visit to Germany is mandatory.

Exam will be conducted during Nashik workshop.

Webinar fees includes all Course Material & Exams fees.

Other expenses to Germany visit shall be borne by the participant.

Last date of registration: 10th January 2019